Comparative epigenetic analysis of tumour initiating cells and neural stem cells in glioblastoma
Introduction and findings Glioblastoma (GBM), an aggressive type of brain tumour, is one of the deadliest forms of cancer. Development of effective therapeutic approaches for GBM faces multiple hurdles, including inter- and intra-tumour cellular and transcriptomic heterogeneity. As a result, remnants of tumour can survive by not reacting to anti-cancer drugs. For example, according to […]