Unveiling the Transcription Factor Circuitry: Resetting the Clock of Life in Early Embryonic Development

Pathos /

Thoughts on Professor Wei Xie’s seminar “Decoding the transcription circuitry when life begins” Deciphering the molecular beginnings of life is fraught with challenges, primarily due to the scarcity of embryonic material available for research. Prof. Wei Xie’s team has advanced our understanding by developing ultra-sensitive chromatin analysis technologies, enabling them to map the chromatin landscape […]

Unveiling the Transcription Factor Circuitry: Resetting the Clock of Life in Early Embryonic Development Read More »

Publication: “Cell-type differential targeting of SETDB1 prevents aberrant CTCF binding, chromatin looping, and cis-regulatory interactions” in Nature Communications

Publications /

The study by Lin Gao et al. in Nature Cell Biology examines the effects of SARS-CoV-2 infection on the maternal-fetal interface using single-cell analysis, revealing significant impacts on transcriptomic and epigenomic profiles. This work provides valuable insights into the consequences of the virus on pregnancy.

Publication: “Cell-type differential targeting of SETDB1 prevents aberrant CTCF binding, chromatin looping, and cis-regulatory interactions” in Nature Communications Read More »

Scroll to Top