H3K27me3-rich Regions Function as Silencers
Introduction and Findings The discovery and validation of human transcriptional silencer elements are scarce. The lack of advance techniques and understanding of their characteristics have resulted in only a handful of silencer discoveries for genes such as human synapsin I, BDNF and CD4. This is in contrast to enhancers and “super-enhancers” of the human genome […]
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